According to the California Highway Patrol logs, the crash near the Lankershim Boulevard off-ramp was reported around 9:10 pm.
CHP issued a SigAlert for the closure of all lanes of the southbound 5 Freeway, bringing traffic to a halt.
The HOV lane and two others were opened about 30 minutes after the initial accident.
Right before 10:30 p.m., all lanes were reopened.
No further details were immediately available.